What is the white "stuff"?

Rogersville, TN

The circles on this plant are on several leaves and seem to be spreading. Can anyone tell me what it is and how to treat it?

Thumbnail by bobbie10
Richland, WA(Zone 7b)

Looks like mildew of some sort-

Burien, WA(Zone 7b)

What kind of plant is that? Gloxinia? If its 1/3 or less of the total foliage, I would start by removing the infected leaves. It does look like a mildew. I use a tea tree oil solution of approximately 10 drops in a pint of water. Spray it on once a week until gone.
There are many home remedies for mildew. http://www.google.com/search?q=home+remedies+for+powdery+mildew+on+plants&ie=UTF-8&oe=UTF-8&hl=en&client=safari

You could also go to a garden center and get a neem oil spray.

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